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SEE VIDEO BY TOPIC: Lab results in thalassemia; How To Diagnose Thalassemia!Content:
ICSE Class 8 Biology Selina Solutions Chapter 8 - Disease and First Aid
Blood disorders can affect any of the components of blood, including red blood cells, white blood cells, platelets, and clotting factors. Blood disorders can also affect the bone marrow, where immature cells called stem cells develop into the specialized cells of blood.
Each component of blood has unique functions. White blood cells help fight infection and cancer. Platelets and clotting factors help the blood to clot, preventing both excessive bleeding and excessive clotting. Problems in the production or functioning of any of these specialized elements of blood can result in a variety of problems. There are many types of anemia, each with its own cause. Some are associated with low production of red blood cells and others are related to an increased breakdown of red blood cells.
Anemia can be temporary or chronic, and it can range from mild to severe. A disorder that interferes with iron metabolism and results in excess iron deposits throughout the body.
The accumulation of iron can cause liver disease, heart failure, diabetes, arthritis, and other serious problems. Hemochromatosis is one of the most common inherited blood disorders. It is treated by removing blood from the body to reduce iron stores. A rare inherited bleeding disorder in which the blood does not clot normally due to absent or low levels of proteins called clotting factors. Severe hemophilia is usually diagnosed in the first year of life, but milder disease may not be diagnosed until adulthood.
Hemophilia is treated with infusions or injections of clotting factors to prevent bleeding or to stop bleeding when it occurs.
A condition in which stem cells produced in the bone marrow fail to mature normally into red blood cells, white blood cells, and platelets. The immature blood cells do not work the way they should and die prematurely. Myelodysplastic syndrome is more common among older adults. In most cases, the cause is unknown. Treatment depends on the clinical situation. A condition in which a greater than normal number of stem cells produced in the bone marrow develop into one or more types of blood cells and the total number of blood cells slowly increases.
There are several types of myeloproliferative disorders, depending on the type of cell or tissue that is increasing excessively. An abnormally low number of neutrophils, a type of white blood cell that helps fight bacterial infections. Neutropenia is not a disease but a sign of an underlying problem, such as a bacterial or viral infection, leukemia, aplastic anemia, or a medication side effect. Treatment involves addressing the underlying cause.
An inherited disease characterized by defective production of hemoglobin, the oxygen-carrying component of blood cells. Severe thalassemia requires regular blood transfusions and folate supplements. Because frequent blood transfusions can result in iron overload, chelation therapy may also be necessary to prevent iron-induced damage to the heart, liver, and other organs.
A blood disorder in which there are not enough platelets, the cells in the blood that help blood to clot. A low platelet count can occur due to low production of platelets in the bone marrow or increased breakdown of platelets in the bloodstream, spleen, or liver.
Treatment depends on the cause of the condition. Call our Help Line: fmhsupport pinehurstmedical. Serving Moore County, North Carolina, and surrounding areas, Pinehurst provides primary and specialty care in fields such as cardiology, dermatology, sleep medicine, and much more. Please click here to view the full policy.
Hematology and Oncology Blood Disorders. Iron deficiency anemia A decrease in the number of red blood cells caused by too little iron, an element that is needed to make hemoglobin. Iron deficiency anemia is the most common type of anemia, especially among women. Causes include an iron-poor diet, poor absorption of iron by the body, and loss of blood due to heavy menstrual bleeding, ulcers, or other causes. Vitamin deficiency anemia Anemia caused by inadequate levels of folic acid or vitamin B, two B vitamins that are needed to form healthy red blood cells.
Pernicious anemia is a type of vitamin B deficiency anemia caused by low levels of intrinsic factor, a protein produced in the gastrointestinal tract that is needed to absorb vitamin B from the stomach. Sickle cell anemia An inherited disease in which the red blood cells are abnormally shaped. These misshapen red blood cells die prematurely, causing a chronic shortage of red blood cells.
They can also cause small blood clots and recurrent painful episodes called sickle cell pain crises. Continuous treatment is necessary to manage and control symptoms and to try to limit the frequency of crises.
Aplastic anemia may be caused by exposure to toxins, radiation, chemotherapy, some medications, and certain viral infections. Depending on the cause, it may be a temporary condition or a chronic disease. Hemolytic anemia An anemia that occurs when red blood cells are destroyed faster than the bone marrow can replace them. Hemolytic anemia may be caused by an inherited illness or defect, an autoimmune disease such as lupus, an infection such as hepatitis, or certain medications such as antibiotics.
In some cases it has no known cause. Hemochromatosis A disorder that interferes with iron metabolism and results in excess iron deposits throughout the body. Hemophilia A rare inherited bleeding disorder in which the blood does not clot normally due to absent or low levels of proteins called clotting factors.
Myelodysplastic syndrome A condition in which stem cells produced in the bone marrow fail to mature normally into red blood cells, white blood cells, and platelets. Myeloproliferative disorder A condition in which a greater than normal number of stem cells produced in the bone marrow develop into one or more types of blood cells and the total number of blood cells slowly increases.
Neutropenia An abnormally low number of neutrophils, a type of white blood cell that helps fight bacterial infections.
Thalassemia An inherited disease characterized by defective production of hemoglobin, the oxygen-carrying component of blood cells. Thrombocytopenia A blood disorder in which there are not enough platelets, the cells in the blood that help blood to clot.
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Anemia is a condition where there are not enough red blood cells. The red blood cells transport oxygen throughout the body. The majority of anemia cases are either hereditary not ratable or caused by another condition, like hypothyroidism.
Blood disorders can affect any of the components of blood, including red blood cells, white blood cells, platelets, and clotting factors. Blood disorders can also affect the bone marrow, where immature cells called stem cells develop into the specialized cells of blood. Each component of blood has unique functions. White blood cells help fight infection and cancer. Platelets and clotting factors help the blood to clot, preventing both excessive bleeding and excessive clotting.
Sickle Cell Trait & Other Hemoglobinopathies & Diabetes (For Providers)
Toggle navigation. Last Updated Stats genes diseases gene-disease associations Data Access API Script Downloads gene-attribute matrix gene-attribute edge list gene set library attribute set library gene similarity matrix attribute similarity matrix gene list attribute list processing scripts gene-attribute matrix cleaned gene-attribute matrix standardized Visualizations Attribute Similarity Dataset Gene Similarity. Pletscher-Frankild, S et al. An adolescence-adult electroclinical syndrome statring between the age of ten to 17 years characterized by the occurrence of typical absence seizures. The presence of multiple cutaneous neurofibromas. A congenital syphilis that occurs in children at or greater than two years of age who acquired the infection trans-placentally. A kidney cancer which is manifested in the kidney. An organic acidemia that involves an accumulation of methylmalonic acid in the blood. A syphilis that is characterized as the second stage of syphilis which appears from 2 to 6 months after primary infection, and is marked by lesions especially in the skin but also in organs and tissues, and that lasts from 3 to 12 weeks. An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently and characterized by an enlarged heart.
Hematology and Oncology Blood Disorders
A new study shows that a protein found in blood alleviates anemia, a condition in which the body's tissues don't get enough oxygen from the blood. In this animal study, injections of the protein, known as transferrin, also protected against potentially fatal iron overload in mice with thalassemia, a type of inherited anemia that affects millions of people worldwide. Implications of the study, published in the January 24 online edition of Nature Medicine, could extend well beyond thalassemia to include other types of anemia including sickle cell anemia and myelodysplastic syndromes bone marrow disorders that often precede leukemia if proven in humans. Fabry, Ph. Our study suggests that treatment with transferrin could prevent this.
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Zinc in Human Biology
Actinic keratosis. Acute coronary syndrome. Acute lymphoblastic or lymphocytic leukemia. Acute lymphocytic leukemia.SEE VIDEO BY TOPIC: Management of Thalassemia
The hemoglobin A1C A1C test can be unreliable for diagnosing or monitoring diabetes and prediabetes in people with inherited hemoglobin variants, also called hemoglobinopathies. These variants interfere with some A1C tests—both laboratory and point-of-care tests. If A1C tests are at odds with blood glucose testing results, interference should be considered. Reliable A1C tests that do not cause interference with hemoglobin variants are available. More information about appropriate assay methods to use for hemoglobin variants is available from the NGSP at www. Also, alternative tests may be needed for people with any disorder that affects red blood cells or hemoglobin.
Blood protein offers help against anemia
Review Questions. Multiple Choice questions: 1. Cataract is a disease of: i Ears ii Nose iii Eyes iv Throat. B3 ii Vit. B1 iii Vit. C iv Vit. Question 1 a.